TRMT6 Recombinant monoclonal antibody proteintech 83843-6-RR
$449.00
In stock
SKU
83843-6-RR
240911D3, CGI 09, CGI-09, mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6, TRM6
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: tRNA methyltransferase 6 homolog (S. cerevisiae) |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 55-60 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: TRMT6 |
| Conjugate: Unconjugated | Gene Symbol: 51605 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671428 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:16000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Transfer RNA (tRNA) modifications help regulate the efficiency of mRNA translation by maintaining the correct reading frames within mRNA. TRMT6 (tRNA methyltransferase 6 ), also known as GCD10 or TRM6, is a 497 amino acid protein that localizes to the nucleus and exists as a heterodimer with TRM61. Expressed in liver, brain, ovary and testis, TRMT6 functions as a substrate-binding subunit of tRNA and is thought to catalyze the formation of N(1)-methyladenine at position 58 in initiator methionyl-tRNA. TRMT6 exists as three alternatively spliced isoforms that, in response to DNA damage, may be phosphorylated by ATM or ATR. |
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