c-SRC Polyclonal antibody proteintech 11097-1-AP
$449.00
In stock
SKU
11097-1-AP
SRC, c SRC, cSRC, EC:2.7.10.2, p60-Src
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse, rat, hamster | Immunogen: CatNo: Ag1575 Product name: Recombinant human c-SRC protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 187-536 aa of BC011566 Sequence: YCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA | Observed Molecular Weight: 60 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC011566 |
| Conjugate: Unconjugated | Gene Symbol: SRC |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 6714 |
| Application: Western Blot (WB) | RRID: ENSG00000197122 |
| Dilution: WB : 1:500-1:3000 | Conjugate: AB_2286705 |
| Tested Reactivity: Human, Mouse, Rat, Hamster | Form: Unconjugated |
| Host / Isotype: Rabbit / IgG | Background Information: SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase. SRC can be detected as 60 kDa and 55 kDa (PMID: 15047935, 21461171). |
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