Transferrin Recombinant monoclonal antibody proteintech 81676-1-RR

$189.00
In stock
SKU
81676-1-RR

 

TF, Serotransferrin, PRO2086, PRO1557, Beta-1 metal-binding globulin

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human, mouse, rat Immunogen: transferrin
 Applications: WB, IHC, ELISA Observed Molecular Weight: 77 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: TF
Conjugate: Unconjugated Gene Symbol: 7018
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_2935573
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human, Mouse, Rat Form: Protein A purification
Host / Isotype: Recombinant Background Information: Serotransferrin(TF) is a 77 kDa secreted protein which is also named as transferrin, siderophilin, beta-1 metal-binding globulin and belongs to a family of homologous iron-binding glycoproteins that encompasses lactoferrin (found both intracellular and in secretions, including milk), melanotrasferrin (present on melanoma cells) and ovotransferrin (present in egg white). TF is a multi-function protein with a primary role in transporting iron in a safe, redox-inactive state from absorption to utilization or storage sites around the body. The association of Tf with the immune system derives from its ability to restrict serum free-iron levels, creating low-iron environments where the infection capacity of pathogenic microorganisms is limited. TF is expressed predominantly in the liver and secreted in plasma, but lower amounts can be synthesized in other tissues such as the brain and the testis.

 

 

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