TRAF6 Recombinant monoclonal antibody proteintech 83535-2-RR
$449.00
In stock
SKU
83535-2-RR
230430H3, E3 ubiquitin-protein ligase TRAF6, EC:2.3.2.27, Interleukin-1 signal transducer, RING-type E3 ubiquitin transferase TRAF6
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: TNF receptor-associated factor 6 |
| Applications: WB, FC (Intra), ELISA | Observed Molecular Weight: 60 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: TRAF6 |
| Conjugate: Unconjugated | Gene Symbol: 7189 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Protein A purification |
| Tested Reactivity: Human | Form: Q9Y4K3 |
| Host / Isotype: Recombinant | Background Information: TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF6 is recognized as a signal transducer, which activates the NF-κB pathway in response to pro-inflammatory cytokines. TRAF6 has E3 ligase activity and is responsible for inducing Lys-63 (K63)-linked poly-ubiquitination chains, functioning together with E2 Ubc13/Uev1A complex to mediate IKK activation TRAF6 plays a crucial role in the regulation of the innate and adaptive immune responses. |
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