Thyroid Hormone Receptor beta Recombinant monoclonal antibody proteintech 83866-2-RR

$449.00
In stock
SKU
83866-2-RR

 

THRB, THR1, NR1A2, ERBA2, c-erbA-beta

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human, mouse Immunogen: thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
 Applications: WB, IF/ICC, FC (Intra), ELISA Observed Molecular Weight: 53 kDa and 54 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: Thyroid Hormone Receptor beta
Conjugate: Unconjugated Gene Symbol: 7068
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3671452
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:200-1:1000 Conjugate: Liquid
Tested Reactivity: Human, Mouse Form: Protein A purfication
Host / Isotype: Recombinant Background Information: Thyroid hormone receptor beta (THRB), also known as ERBA2,?NR1A2,?and THR1, belongs to the?nuclear hormone receptor family and?NR1 subfamily. THRB is a nuclear hormone receptor that can act as a repressor or activator of transcription. Moreover, THRB is also a high-affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. THRB is the most abundant THR isoform in the liver but is also expressed in other tissues and mediates the effects of THs on hepatic carbohydrate and lipid metabolism (PMID:?34884910). THRB has 2 isoforms with the molecular mass of 53 and 54 kDa (refer to UniProt).

 

 

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