TFPI Recombinant monoclonal antibody proteintech 83838-5-RR

$449.00
In stock
SKU
83838-5-RR

 

240977B1, EPI, Extrinsic pathway inhibitor, LACI, Lipoprotein-associated coagulation inhibitor

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human Immunogen: tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
 Applications: WB, IF/ICC, FC (Intra), ELISA Observed Molecular Weight: 40 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: TFPI
Conjugate: Unconjugated Gene Symbol: 7035
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3671421
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human Form: Protein A purfication
Host / Isotype: Recombinant Background Information: Tissue factor pathway inhibitor (TFPI) is a critical anticoagulant protein present in endothelium and platelets. TFPI is produced as two major isoforms in humans, TFPIa and TFPIb that result from alternative splicing. The TFPIb isoform localizes to the endothelium surface where it is a potent inhibitor of tissue factor-factor VIIa complexes that initiate blood coagulation. The TFPIa isoform is present in platelets. TFPI is a Kunitz-type serine protease inhibitor that exerts anticoagulant activity by blocking early procoagulant stimulia. TFPI can enhance anti-thrombotic treatment in sepsis, inflammatory diseases, and cardiovascular diseases.

 

 

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