SMC6 Recombinant monoclonal antibody proteintech 83187-3-RR
$449.00
In stock
SKU
83187-3-RR
240015F4, hSMC6, SMC 6, SMC protein 6, SMC-6
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: structural maintenance of chromosomes 6 |
| Applications: WB, IF-P, FC (Intra), ELISA | Observed Molecular Weight: 130 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: SMC6 |
| Conjugate: Unconjugated | Gene Symbol: 79677 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670876 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: SMC6 (Structural maintenance of chromosomes protein 6) is core component of the SMC5-SMC6 complex that is involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs) (PMID: 26983541). |
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