SIRP Alpha/CD172a Recombinant monoclonal antibody proteintech 84430-2-RR
$449.00
In stock
SKU
84430-2-RR
Inhibitory receptor SHPS-1, CD172a, CD172 antigen-like family member A, Brain Ig-like molecule with tyrosine-based activation motifs, Bit
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: mouse | Immunogen: signal-regulatory protein alpha |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 90-140 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Sirpa |
| Conjugate: Unconjugated | Gene Symbol: 19261 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671957 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Mouse | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: SIRP Alpha, also known as CD172a, SHPS-1, and BIT, belongs to the SIRP family. SIRP Alpha is a transmembrane glycoprotein expressed explicitly on myeloid cells and provides a "do not eat me" signal after engaging with integrin-associated protein CD47 on tumor cells (PMID: 36419386). SIRP Alpha shows heterogeneity in molecular weight (~65-120 kDa) in various tissues due to differential glycosylation (PMID: 18051954). |
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