SIRP Alpha/CD172a Recombinant monoclonal antibody proteintech 83729-5-RR
$449.00
In stock
SKU
83729-5-RR
SIRP Alpha, SIRPA, Inhibitory receptor SHPS-1, CD172a, CD172 antigen-like family member A
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: signal-regulatory protein alpha |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 75-85 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: SIRP Alpha |
| Conjugate: Unconjugated | Gene Symbol: 140885 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671328 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: SIRP Alpha, also known as CD172a, SHPS-1, and BIT, belongs to the SIRP family. SIRP Alpha is a transmembrane glycoprotein expressed explicitly on myeloid cells and provides a "do not eat me" signal after engaging with integrin-associated protein CD47 on tumor cells (PMID:?36419386). SIRP Alpha shows heterogeneity in molecular weight (~65-120 kDa) in various tissues due to differential glycosylation (PMID: 18051954). |