SIRP Alpha/CD172a Recombinant monoclonal antibody proteintech 83729-5-RR

$449.00
In stock
SKU
83729-5-RR

 

SIRP Alpha, SIRPA, Inhibitory receptor SHPS-1, CD172a, CD172 antigen-like family member A

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human Immunogen: signal-regulatory protein alpha
 Applications: WB, IF/ICC, ELISA Observed Molecular Weight: 75-85 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: SIRP Alpha
Conjugate: Unconjugated Gene Symbol: 140885
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3671328
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human Form: Protein A purfication
Host / Isotype: Recombinant Background Information: SIRP Alpha, also known as CD172a, SHPS-1, and BIT, belongs to the SIRP family. SIRP Alpha is a transmembrane glycoprotein expressed explicitly on myeloid cells and provides a "do not eat me" signal after engaging with integrin-associated protein CD47 on tumor cells (PMID:?36419386). SIRP Alpha shows heterogeneity in molecular weight (~65-120 kDa) in various tissues due to differential glycosylation (PMID: 18051954).

 

 

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