SCN4A Recombinant monoclonal antibody proteintech 85698-1-RR
$449.00
In stock
SKU
85698-1-RR
HYKPP, HYPP, Na(V)1.4, NAC1A, Nav1.4
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: sodium channel, voltage-gated, type IV, alpha subunit |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 208 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: SCN4A |
| Conjugate: Unconjugated | Gene Symbol: 6329 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse | Form: P35499 |
| Host / Isotype: Recombinant | Background Information: Sodium channel protein type 4 subunit alpha?(SCN4A, also known as Nav1.4) is the pore-forming subunit of the primary sodium channel present in skeletal muscles (PMID: 16193245). Nav1.4 related channelopathies that affect skeletal muscle excitability are dominant diseases classified in two opposite groups as defined by the prevalent clinical symptoms: muscle stiffness and hypertonia (myotonia) episodes [non dystrophic myotonias (NDM)], and muscle weakness resulting in paralysis episodes (periodic paralyses; PP) (PMID: 20237798; 26285000). |
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