CD34 Polyclonal antibody proteintech 14486-1-AP

$449.00
In stock
SKU
14486-1-AP

 

CD34 molecule

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human And More (4) Immunogen: CatNo: Ag5887 Product name: Recombinant human CD34 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 34-287 aa of BC039146 Sequence: DNNGTATPELPTQGTFSNVSTNVSYQETTTPSTLGSTSLHPVSQHGNEATTNITETTVKFTSTSVITSVYGNTNSSVQSQTSVISTVFTTPANVSTPETTLKPSLSPGNVSDLSTTSTSLATSPTKPYTSSSPILSDIKAEIKCSGIREVKLTQGICLEQNKTSSCAEFKKDRGEGLARVLCGEEQADADAGAQVCSLLLAQSEVRPQCLLLVLANRTEISSKLQLMKKHQSDLKKLGILDFTEQDVASHQSYS Predict reactive species
 Applications: WB, IHC, IF-P, ELISA Observed Molecular Weight: 41 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC039146
Conjugate: Unconjugated Gene Symbol: CD34
Tested Applications: Positive WB detected in Gene ID (NCBI): 947
Application: Western Blot (WB) RRID: AB_2228975
Dilution: WB : 1:500-1:3000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: CD34 is a 105- to 120-kDa glycophosphoprotein expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nerve tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells and mediates cell adhesion and lymphocyte homing by binding L-selectin and E-selectin ligands. CD34 is also one of the best negative selection markers for characterizing and/or isolating human MSCs from bone marrow and other sources. Along with other positive selection markers (such as CD29, CD44, CD90, CD105 and CD166), negative selection markers (such as CD34 and CD45) are used for MSC identification. The calculated molecular mass of human CD34 is 41 kDa, various forms with different molecular weights may be produced due to different glycosylation patterns and alternative splicing (PMID: 24375067; 15750786).

 

 

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