RCN1 Recombinant monoclonal antibody proteintech 83638-3-RR
$449.00
In stock
SKU
83638-3-RR
Reticulocalbin 1, 240473E9, PIG20, RCAL, RCN
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: reticulocalbin 1, EF-hand calcium binding domain |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 44-46 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: RCN1 |
| Conjugate: Unconjugated | Gene Symbol: 5954 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671250 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Reticulocalbin-1 (RCN1) belongs to?the?CREC family. Reticulocalbin‐1, an endoplasmic reticulum protein, plays a crucial role in calcium homeostasis and inhibits ER stress‐induced apoptosis (PMID: 28319095). Its main functions include maintaining intracellular homeostasis and regulating cell proliferation and apoptosis, and it plays an important role in the development of various tumours (PMID: 38057406). RCN1 is expressed aberrantly and at a high level in various tumors, including acute myeloid leukemia (AML) (PMID: 37746742). In multiple cancers, such as glioblastoma, non‐small cell lung cancer, renal cell carcinoma, hepatocellular carcinoma, and oral squamous cell carcinoma, the overexpression of?RCN1?has been observed indicating its involvement in tumorigenesis and invasion (PMID: 30172915, PMID: 34722631). |
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