PSIP1 Recombinant monoclonal antibody proteintech 85395-1-RR
$449.00
In stock
SKU
85395-1-RR
242841C5, CLL associated antigen KW 7, CLL-associated antigen KW-7, DFS70, LEDGF
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: PC4 and SFRS1 interacting protein 1 |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 75 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: PSIP1 |
| Conjugate: Unconjugated | Gene Symbol: 11168 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse, Rat | Form: O75475 |
| Host / Isotype: Recombinant | Background Information: PSIP1, also known as PC4 and SRSF1 Interacting Protein 1 or Lens Epithelium-Derived Growth Factor (LEDGF), is a transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. It also plays a role in lens epithelial cell gene regulation and stress responses. It is a chromatin-associated protein with histone chaperone activity, involved in transcriptional elongation. PSIP1 may act as an adapter to coordinate pre-mRNA splicing. PSIP1 encodes two protein isoforms with molecular masses of 52 and 75 kDa. p52 and p75 were identified as interacting with transcription factor PC4 and shown to act as transcriptional coactivators. |
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