PRMT5 Recombinant monoclonal antibody proteintech 82750-3-RR
$449.00
In stock
SKU
82750-3-RR
72 kDa ICln-binding protein, EC:2.1.1.320, Histone-arginine N-methyltransferase PRMT5, Jak-binding protein 1, Protein arginine N methyltransferase 5
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: protein arginine methyltransferase 5 |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 67-70 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: PRMT5 |
| Conjugate: Unconjugated | Gene Symbol: 10419 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:20000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse, Rat | Form: O14744 |
| Host / Isotype: Recombinant | Background Information: PRMT5 is a Type II enzyme that catalyzes arginine monomethylation and symmetric dimethylation (Rme1 and Rme2s). The many targets of PRMT5 include ribosomal proteins, the histone chaperone nucleoplasmin, p53, and histones. PRMT5?is frequently observed in a complex with the cofactor, methylosome protein 50 (MEP50), which is required for?PRMT5?activity. PRMT5 is upregulated in several human malignancies, including lymphomas, lung cancer, breast cancer and colorectal cancer. |
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