NSUN2 Recombinant monoclonal antibody proteintech 82894-7-RR
$449.00
In stock
SKU
82894-7-RR
RNA cytosine C(5)-methyltransferase NSUN2, Myc-induced SUN domain-containing protein, mRNA cytosine C(5)-methyltransferase, EC:2.1.1.-, EC:2.1.1.203, EC:2.1.1.-
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: NOL1/NOP2/Sun domain family, member 2 |
| Applications: WB, IHC, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 90-100 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NSUN2 |
| Conjugate: Unconjugated | Gene Symbol: 54888 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670623 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: NSUN2, also known as SAKI or Misu (Myc-induced SUN-domain-containing protein), is a methyltransferase which catalyses (cytosine-5-)-methylation of tRNA. NSUN2 is direct target gene of c-Myc and may act downstream of Myc to regulate epidermal cell growth and proliferation. NSUN2 is overexpressed in various cancer tissues and may be a valuable target for cancer therapy and a cancer diagnostic marker. Recently a splicing mutation in NSUN2 has been identified as the cause of a Dubowitz-like syndrome, an autosomal recessive disorder. |
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