Neuropilin 1/CD304 Recombinant monoclonal antibody proteintech 84429-5-RR
$449.00
In stock
SKU
84429-5-RR
neuropilin 1, NRP1, 241812G11, BDCA4, CD304
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: neuropilin 1 |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: BC007533 |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: 8829 |
| Conjugate: Unconjugated | Gene Symbol: AB_3671956 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:500-1:2000 | Conjugate: Protein A purfication |
| Tested Reactivity: Human, Mouse, Rat | Form: O14786 |
| Host / Isotype: Recombinant | Background Information: Neuropilin-1 (NRP1) is a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion. |
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