Neurogranin Recombinant monoclonal antibody proteintech 83593-5-RR
$449.00
In stock
SKU
83593-5-RR
NRGN, 240526B9, hng, NEUG(55-78), Ng
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: neurogranin (protein kinase C substrate, RC3) |
| Applications: WB, IHC, IF-P, FC (Intra), ELISA | Observed Molecular Weight: 15-17 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Neurogranin |
| Conjugate: Unconjugated | Gene Symbol: 4900 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671208 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Neurogranin (formerly designated p17, also known as Ng, RC3 and BICKS) belongs to the neurogranin family. It is a neuron-specific substrate for protein kinase C (PKC). It is a postsynaptic protein that is highly enriched in brain, with restricted expression in the cortex, striatum, hippocampus, thalamus, hypothalamus and olfactory bulb nuclei. Neurogranin binds calmodulin at low levels of calcium, thereby regulating calmodulin-dependent nitric oxide synthase. Neurogranin acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. It binds to calmodulin in the absence of calcium. |
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