MAP2 Recombinant monoclonal antibody proteintech 84306-4-RR
$449.00
In stock
SKU
84306-4-RR
241653H8, MAP 2, MAP-2, MAP2A, MAP2B
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: microtubule-associated protein 2 |
| Applications: WB, IF/ICC, IF-P, IF-Fro, ELISA | Observed Molecular Weight: 280-300 kDa, 70-85 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: MAP2 |
| Conjugate: Unconjugated | Gene Symbol: 4133 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671847 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: MAP2 (microtubule-associated protein 2) is a cytoskeleton protein abundant in the brain and has an important role in neuronal morphogenesis. Multiple high MW and low MW MAP2 isoforms are expressed within the proximal segment of axons, dendrites, and cell bodies. The expression of MAP2 is regulated in both a tissue- and developmentally-specific manner. The 280 kDa MAP2B is present throughout rat brain development, and the slightly larger MAP2A appears first during the end of the second week of postnatal life. MAP2C, composed of several bands of about 70 kDa, is present during early brain development and largely disappears from the mature brain except for the retina, olfactory bulb, and cerebellum. In addition, some isoforms with lower MW around 50-60 kDa also exist. MAP2 antibodies have been widely used to mark the neuron or dendrite formation. |