Lamin B2 Recombinant monoclonal antibody proteintech 82801-4-RR
$449.00
In stock
SKU
82801-4-RR
LMNB2, 230184C7, LAMB2, Lamin-B2, LMN2
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: lamin B2 |
| Applications: WB, IHC, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 68 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Lamin B2 |
| Conjugate: Unconjugated | Gene Symbol: 84823 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670555 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Lamins are nuclear membrane structural components that are important in structural integrity of the nucleus and may also interact with chromatin (PMID: 33033404). Research studies show that lamin B2 knockout mice exhibit neuronal developmental defects and that both proteins are essential for typical brain development (PMID: 20145110). Mutations in Lamin B2 can result in a susceptibility to developing acquired partial lipodystrophy, a rare disorder characterized by the progressive loss of subcutaneous fat in a bilaterally symmetrical fashion (PMID: 16826530). |
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