KIF5B Recombinant monoclonal antibody proteintech 82485-1-RR
$449.00
In stock
SKU
82485-1-RR
KNS1, KNS, KINH, Kinesin-1 heavy chain, KIF 5B
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: kinesin family member 5B |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 110-120 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: KIF5B |
| Conjugate: Unconjugated | Gene Symbol: 3799 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3086482 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: KIF5B, also known as KINH, KNS1, belongs to the Kinesin-1 family. KIF5B contains three structural domains: a globular N-terminal motor domain, a central alpha-helical rod domain, and a globular C-terminal domain. During the G2 phase of the cell cycle in a BICD2-dependent manner, KIF5B antagonizes the dynein function and drives the separation of nuclei and centrosomes (PMID: 20386726). KIF5B drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells (KIF5B:24088571). |
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