Integrin alpha-5/CD49e Recombinant monoclonal antibody proteintech 84468-4-RR
$449.00
In stock
SKU
84468-4-RR
Integrin Alpha-5, ITGA5, 241685A3, CD49 antigen-like family member E, CD49e
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, pig | Immunogen: integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 140 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Integrin alpha 5 |
| Conjugate: Unconjugated | Gene Symbol: 3678 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671991 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Pig | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha 5 (ITGA5), belongs to the integrin alpha chain family, primarily binds to Integrin beta 1 (ITGB1) to form an α5β1 heterodimer (PMID: 33711961). Integrin α5β1 is a specific receptor of fibronectin through its arginine-glycine-aspartic acid (RGD) binding site (PMID: 19608542). Integrin α5β1 plays roles in cell adhesion, migration and matrix formation, and has emerged as an essential mediator in many human carcinomas (PMID: 33408483). |