Integrin Alpha V Recombinant monoclonal antibody proteintech 84883-5-RR
$449.00
In stock
SKU
84883-5-RR
ITGAV, 242376D3, CD51, Integrin alpha-V, Integrin alpha-V heavy chain
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) |
| Applications: WB, IHC, IF/ICC, FC, ELISA | Observed Molecular Weight: 130 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Integrin alpha V |
| Conjugate: Unconjugated | Gene Symbol: 3685 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: P06756 |
| Host / Isotype: Recombinant | Background Information: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha V, also known as CD51, is a type I transmembrane glycoprotein composed of an extracellular domain, a transmembrane region and cytoplasmic domain (PMID: 2430295; 1690718). It can form heterodimers with one of the five beta integrin subunits (beta 1, 3, 5, 6, 8) that recognize ligands containing the sequence Arg-Gly-Asp, such as vitronectin, fibronectin, and osteopontin (PMID: 37087799). Integrin alpha V mainly plays a role in extracellular matrix-mediated cell adhesion and migration, differentiation, wound healing, inflammation, tumorigenesis, proliferation, angiogenesis, and metastasis. |