Integrin Alpha V Recombinant monoclonal antibody proteintech 84883-5-RR

$449.00
In stock
SKU
84883-5-RR

 

ITGAV, 242376D3, CD51, Integrin alpha-V, Integrin alpha-V heavy chain

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human Immunogen: integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
 Applications: WB, IHC, IF/ICC, FC, ELISA Observed Molecular Weight: 130 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: Integrin alpha V
Conjugate: Unconjugated Gene Symbol: 3685
Tested Applications: Positive WB detected in Gene ID (NCBI): Unconjugated
Application: Western Blot (WB) RRID: Liquid
Dilution: WB : 1:5000-1:50000 Conjugate: Protein A purfication
Tested Reactivity: Human Form: P06756
Host / Isotype: Recombinant Background Information: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha V, also known as CD51, is a type I transmembrane glycoprotein composed of an extracellular domain, a transmembrane region and cytoplasmic domain (PMID: 2430295; 1690718). It can form heterodimers with one of the five beta integrin subunits (beta 1, 3, 5, 6, 8) that recognize ligands containing the sequence Arg-Gly-Asp, such as vitronectin, fibronectin, and osteopontin (PMID: 37087799). Integrin alpha V mainly plays a role in extracellular matrix-mediated cell adhesion and migration, differentiation, wound healing, inflammation, tumorigenesis, proliferation, angiogenesis, and metastasis.

 

 

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