IDH1 Recombinant monoclonal antibody proteintech 81176-1-RR

$449.00
In stock
SKU
81176-1-RR

 

6L18, Cytosolic NADP-isocitrate dehydrogenase, EC:1.1.1.42, IDCD, IDH

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human, mouse, rat Immunogen: isocitrate dehydrogenase 1 (NADP+), soluble
 Applications: WB, IHC, FC (Intra), ELISA Observed Molecular Weight: 46 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: IDH1
Conjugate: Unconjugated Gene Symbol: 3417
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_2923706
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human, Mouse, Rat Form: Protein A purification
Host / Isotype: Recombinant Background Information: IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171). IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).

 

 

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