IDH1 Recombinant monoclonal antibody proteintech 81176-1-RR
$449.00
In stock
SKU
81176-1-RR
6L18, Cytosolic NADP-isocitrate dehydrogenase, EC:1.1.1.42, IDCD, IDH
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: isocitrate dehydrogenase 1 (NADP+), soluble |
| Applications: WB, IHC, FC (Intra), ELISA | Observed Molecular Weight: 46 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: IDH1 |
| Conjugate: Unconjugated | Gene Symbol: 3417 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2923706 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171). IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ). |