MX1 Polyclonal antibody proteintech 13750-1-AP
$449.00
In stock
SKU
13750-1-AP
IFI-78K, Interferon-induced GTP-binding protein Mx1, Interferon-induced GTP-binding protein Mx1, N-terminally processed, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse And More (7) | Immunogen: CatNo: Ag4692 Product name: Recombinant human MX1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 312-662 aa of BC032602 Sequence: LLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLIIQFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), IP, ELISA | Observed Molecular Weight: 662 aa, 76 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC032602 |
| Conjugate: Unconjugated | Gene Symbol: MX1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 4599 |
| Application: Western Blot (WB) | RRID: AB_2266768 |
| Dilution: WB : 1:500-1:1000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Mx1 (also known as MxA) is a GTPase that belongs to the Mx family of proteins, which are ubiquitous in eukaryotes and involved in the immune response to viral infections. The human Mx1 is localized in the cytoplasm interfering with the translation of viral proteins, whereas the mouse Mx1 accumulates in the nucleus and inhibits the primary transcription of viral RNA. Mx1 expression is induced by treatment with α/β IFN. This antibody can recognize the endogenous Mx1 protein in several tissues like lung and spleen. |