FANCD2 Recombinant monoclonal antibody proteintech 83946-4-RR
$449.00
In stock
SKU
83946-4-RR
241048G8, FA4, FACD, FAD, FAD2
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: Fanconi anemia, complementation group D2 |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 150-160 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: FANCD2 |
| Conjugate: Unconjugated | Gene Symbol: 2177 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671526 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Amongst the FA genes, Fanconi Anemia Group D2 Protein (FANCD2) is the most evolutionarily conserved gene, demonstrating a high sequence similarity from lower eukaryotes to humans. Upon activation, Fanconi anemia group D2 protein (FANCD2) is monoubiquitinated at K561 and works in cooperation with other FA and non-FA proteins to repair DNA damage. In regards to the FA pathway, monoubiquitinated or activated FANCD2 is often portrayed as the functional representative for the functions of activated FA signaling. (PMID: 28825622) |
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