ELK1 Recombinant monoclonal antibody proteintech 87009-2-RR
$449.00
In stock
SKU
87009-2-RR
ELK, ELK 1, ETS domain-containing protein Elk-1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: ELK1, member of ETS oncogene family |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 58-60 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: ELK1 |
| Conjugate: Unconjugated | Gene Symbol: 2002 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human | Form: P19419 |
| Host / Isotype: Recombinant | Background Information: ELK1 is a nuclear transcription factor of the ETS-domain family and the ternary complex factor (TCF) sub-family. It binds to purine-rich DNA sequences and forms a ternary complex with serum response factor (SRF) on the serum response element (SRE) located in the promoter regions of immediate early genes such as FOS and IER2. Upon activation of the JNK or MAPK/ERK signaling cascades, ELK1 is phosphorylated and rapidly induces target-gene transcription, thereby regulating cell proliferation, differentiation, and survival. |
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