EIF2AK1 Recombinant monoclonal antibody proteintech 81768-1-RR
$449.00
In stock
SKU
81768-1-RR
3J9, EC:2.7.11.1, Eukaryotic translation initiation factor 2-alpha kinase 1, HCR, Heme controlled repressor
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: eukaryotic translation initiation factor 2-alpha kinase 1 |
| Applications: WB, ELISA | Observed Molecular Weight: 71 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: EIF2AK1 |
| Conjugate: Unconjugated | Gene Symbol: 27102 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2935578 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Eukaryotic initiation factor 2a (eIF2a), which is a critical component in the formation of the translation initiation ternary complex (eIF2a/GTP/methionyl transfer RNA), plays a key role in the ER stress response. EIF2AK1, which is activated by heme deficiency and other stimuli, is a major kinase that phosphorylates EIF2-alpha. Phosphorylation of the alpha subunit of EIF2 downregulates protein synthesis in response to various stress conditions. |
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