EGLN3 Recombinant monoclonal antibody proteintech 82377-1-RR
$449.00
In stock
SKU
82377-1-RR
EGLN3/PHD3, PHD3, 1O19, EC:1.14.11.-, EC:1.14.11.29
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: egl nine homolog 3 (C. elegans) |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 27-30 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: EGLN3 |
| Conjugate: Unconjugated | Gene Symbol: 112399 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670522 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: EGLN3, also named as HPH-1, HIF-PH3, HPH-3 and PHD3, is a cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. It hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. It is a regulator of cardiomyocyte and neuronal apoptosis. EGLN3 can be a prognostic marker for gastric cancer. |
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