EGFR Recombinant monoclonal antibody proteintech 83806-1-RR
$449.00
In stock
SKU
83806-1-RR
EGFR-Specific, 240603F10, EGF R, EGF Receptor , Epidermal growth factor receptor
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) |
| Applications: WB, IHC, IHC-Autostainer, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 145-165 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: EGFR |
| Conjugate: Unconjugated | Gene Symbol: 1956 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671393 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: EGFR, also named as ERBB1, is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12, encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. Mutations in this gene are associated with lung cancer. |
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