Cytokeratin 10 Recombinant monoclonal antibody proteintech 86324-1-RR
$449.00
In stock
SKU
86324-1-RR
KRT10, CK 10, CK10, CK-10, Cytokeratin,Keratin
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: keratin 10 |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 59 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Cytokeratin 10 |
| Conjugate: Unconjugated | Gene Symbol: 3858 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse, Rat | Form: P13645 |
| Host / Isotype: Recombinant | Background Information: Cytokeratin 10 (CK-10, K10, KRT10) is a type I (acidic) cytokeratin and part of the intermediate filament protein superfamily. It is expressed in keratinized stratified epithelium, suprabasal cell layers (including the stratum corneum), and differentiated areas of highly differentiated squamous cell carcinomas. CK-10 plays a role in maintaining the structural integrity of epithelial cells and is involved in differentiation, tissue specialization, and epidermal barrier establishment. Mutations in the KRT10 gene are associated with epidermolytic hyperkeratosis, and its expression is linked to the terminal differentiation of epidermal cells . CK-10 is also used as a marker for tissue differentiation and characterization of malignant tumors in surgical pathology. |
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