Cyclin E1 Recombinant monoclonal antibody proteintech 82700-10-RR
$449.00
In stock
SKU
82700-10-RR
CCNE1, G1/S-specific cyclin-E1, G1/S specific cyclin E1, Cyclin E, CCNE
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, rat | Immunogen: cyclin E1 |
| Applications: WB, FC (Intra), ELISA | Observed Molecular Weight: 45 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Cyclin E1 |
| Conjugate: Unconjugated | Gene Symbol: 898 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670531 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:2000 | Conjugate: Liquid |
| Tested Reactivity: Human, Rat | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Cyclin E1 (CCNE1) is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNE1, an essential cyclin activating Cdk2, regulates the G1-S phase transition of the mammalian cell division cycle. Its timing expression plays a direct role in the initiation of DNA replication , the control of histone biosynthesis, and the centrosome cycle. CCNE1 is associated with disease progression in various malignancies and is associated clinically with poor prognosis. Two bands of Cyclin E1 were expressed in U2OS and MDA-MB-231 cells (PMID:9858585, PMID: 24112607). |
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