CKAP2L Recombinant monoclonal antibody proteintech 86247-1-RR
$449.00
In stock
SKU
86247-1-RR
Cytoskeleton-associated protein 2-like, Radial fiber and mitotic spindle protein, Radmis
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: cytoskeleton associated protein 2-like |
| Applications: WB, IF/ICC, IP, ELISA | Observed Molecular Weight: 84 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CKAP2L |
| Conjugate: Unconjugated | Gene Symbol: 150468 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Protein A purification |
| Tested Reactivity: Human | Form: Q8IYA6 |
| Host / Isotype: Recombinant | Background Information: CKAP2L is a microtubule-binding protein that is crucial for the formation of the mitotic spindle and the cell cycle progression of neural progenitor cells. Mutations in CKAP2L have been associated with spindle organization defects, including mitotic spindle defects, lagging chromosomes, and chromatin bridges. There is evidence that mutations in this gene are associated with Filippi syndrome, characterized by growth defects, microcephaly, intellectual disability, facial feature defects, and syndactyly(PMID: 25439729). |
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