CCL20/MIP-3 alpha Recombinant monoclonal antibody proteintech 84413-3-RR

$449.00
In stock
SKU
84413-3-RR

 

CCL20, MIP-3 Alpha, MIP-3α, 241694B4, Beta-chemokine exodus-1

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human, mouse Immunogen: chemokine (C-C motif) ligand 20
 Applications: WB, IHC, ELISA Observed Molecular Weight: 11 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: CCL20/MIP-3 alpha
Conjugate: Unconjugated Gene Symbol: 6364
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3671942
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human, Mouse Form: Protein A purification
Host / Isotype: Recombinant Background Information: CCL20, also known as macrophage in?ltrating factor protein 3α, is a C-C chemokine that speci?cally binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.

 

 

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