calreticulin Recombinant monoclonal antibody proteintech 80017-1-RR
$449.00
In stock
SKU
80017-1-RR
CALR, Calregulin, 2B17
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: calreticulin |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 50-55 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Calreticulin |
| Conjugate: Unconjugated | Gene Symbol: 811 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2882941 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CALR,also named as grp60, ERp60, HACBP, CRP55, CRTC and Calregulin, belongs to the calreticulin family. It is a molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. CALR is a ER marker. It interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. CALR interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. The MW of CALR migrates aberrantly at 55 kDa by SDS-PAGE. Some study provided that it's a new possibility for CRT-mediated tumor immune prevention and treatment. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
