Beta galactosidase Recombinant monoclonal antibody proteintech 83706-6-RR
$449.00
In stock
SKU
83706-6-RR
GLB1, 240788F1, Acid beta-galactosidase, Beta-galactosidase, EBP
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: galactosidase, beta 1 |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 62-67 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: GLB1/Beta-galactosidase |
| Conjugate: Unconjugated | Gene Symbol: 2720 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671308 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: GLB1(Beta-galactosidase) is also named as ELNR1 or Lactase. It cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. This protein is identical to the elastin-binding protein (EBP), a major component of the nonintegrin cell surface receptor complex expressed in fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. Defects in GLB1 are the cause of GM1-gangliosidosis type 1 (GM1G1), GM1-gangliosidosis type 2 (GM1G2), GM1-gangliosidosis type 3 (GM1G3) and mucopolysaccharidosis type 4B (MPS4B). GBL1 is synthesized as an 85-kDa precursor that is C-terminally processed into a 64-66 kDa mature form and the released ~20-kDa proteolytic fragment was thought to be degraded (PMID: 10744681). The MW of GLB1 after glycosylation is 100-120 kd. GLB1 is prone to produce homodimers (220-240 kd) and higher multimers (PMID: 3926488). GLB1 has 3 isoforms with MW of 76 kDa, 73 kda, and 61 kDa. |
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