B7-H4 Recombinant monoclonal antibody proteintech 82850-1-RR

$449.00
In stock
SKU
82850-1-RR

 

VTCN1, B7?H4, B7H4, B7h.5, B7 homolog 4

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human, mouse Immunogen: V-set domain containing T cell activation inhibitor 1
 Applications: WB, IHC, ELISA Observed Molecular Weight: 75 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: B7-H4
Conjugate: Unconjugated Gene Symbol: 79679
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3670576
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:1000-1:5000 Conjugate: Liquid
Tested Reactivity: Human, Mouse Form: Protein A purification
Host / Isotype: Recombinant Background Information: B7-H4, also named VTCN1, B7X, or B7S1, is a single-pass type I membrane protein, which contains two immunoglobulin-like domains and belongs to the immunoglobulin superfamily. B7-H4 negatively regulates T-cell mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. B7-H4 is over-expressed in many cancers, including breast, ovarian, endometrial, renal cell and non-small-cell lung cancers. The predicted molecular weight of B7?H4 is 31 kDa. The glycosylated B7?H4 is 50 to 80 kDa, and the non-glycosylated form is 28 kDa.

 

 

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