ATOX1 Recombinant monoclonal antibody proteintech 83785-6-RR
$449.00
In stock
SKU
83785-6-RR
ATX1, ATOX 1, Antioxidant?1, 240679E9
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: ATX1 antioxidant protein 1 homolog (yeast) |
| Applications: WB, FC (Intra), ELISA | Observed Molecular Weight: 7 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: ATOX1 |
| Conjugate: Unconjugated | Gene Symbol: 475 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671377 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Antioxidant?1 (ATOX1) is a copper chaperone to regulate copper homeostasis in cell. In the cytosol, ATOX1 always binds to copper and transfer to ATPase proteins in the trans-Golgi network, thereby promoting copper supply to various copper-dependent oxidereductases matured within the secretory vesicles (PMID: 28294521). Also, the protein could protect cells against oxidative damage and the expression levels of ATOX1 may help to the inflammatory response and antioxidant defense,even to modulate response to the cancer (PMID:?27472369). ATOX1 plays an important role in the physiology of the human central nervous system?,and it's highly expressed in the cerebral cortex and hippocampus (PMID: 30545441). Either cytosol or nucleus location of ATOX1 has been reported in different literations, which may be associated with cell status (PMID: 24445997; 31317143). |
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