USP53 Recombinant monoclonal antibody proteintech 83846-1-RR
$449.00
In stock
SKU
83846-1-RR
KIAA1350, Inactive ubiquitin-specific peptidase 53, Inactive ubiquitin carboxyl-terminal hydrolase 53, 240971A6
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: human | Immunogen: CatNo: Ag28923 Product name: Recombinant human USP53 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 371-600 aa of NM_019050 Sequence: YKSVAENMGCEKPVIHKSDNLKENGFGDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSES Predict reactive species |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 121 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_019050 |
| Conjugate: Unconjugated | Gene Symbol: USP53 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 54532 |
| Application: Western Blot (WB) | RRID: AB_3671432 |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Ubiquitin specific peptidase 53 (USP53) was originally discovered in cholestasis, and its tumor suppressive effects have recently been reported in various cancers. Zhao et al. showed that USP53 interacted with FKBP51 in lung adenocarcinoma cells, and induced apoptosis via the AKT pathway. Furthermore, USP53 inhibited the progression of clear cell renal cell carcinoma by suppressing the nuclear factor κB (NF‐κB) pathway. (PMID: 35654790) |
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