SORBS2 Recombinant monoclonal antibody proteintech 83189-3-RR
$449.00
In stock
SKU
83189-3-RR
Sorbin and SH3 domain-containing protein 2, ArgBP2, Arg-binding protein 2, Arg/Abl-interacting protein 2, 240023A8
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: human | Immunogen: CatNo: Ag20041 Product name: Recombinant human SORBS2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-198 aa of BC011883 Sequence: MSYYQRPFSPSAYSLPASLNSSIVMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTPYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDRSSTEKHDWDPPDR Predict reactive species |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 1100 aa, 124 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC011883 |
| Conjugate: Unconjugated | Gene Symbol: SORBS2 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 8470 |
| Application: Western Blot (WB) | RRID: AB_3670879 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: SORBS2, also known as ARGBP2, has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. SORBS2 is widely expressed in human tissues and extremely abundant in the heart. In epithelial cells SORBS2 is located in stress fibers and the nucleus; In cardiac muscle cells. SORBS2 is located in the Z-disks of sarcomeres. The subcellular localization suggests that SORBS2 functions as an adapter protein to assemble signaling complexes in stress fibers, and may influence the contractile or elastic properties of cardiac sarcomeres(PMID: 9211900). Alternate splicing results in multiple transcript variants( PMID: 28961272). |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
