TRIM63 Polyclonal antibody proteintech 55456-1-AP
$449.00
In stock
SKU
55456-1-AP
MuRF1, MuRF 1, Iris RING finger protein, IRF, EC:2.3.2.27
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (5) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF/ICC, IF-P, ELISA | Observed Molecular Weight: 40 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_032588 |
| Conjugate: Unconjugated | Gene Symbol: TRIM63 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 84676 |
| Application: Western Blot (WB) | RRID: AB_11232209 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: TRIM63, also named as IRF, MURF1, RNF28 and SMRZ, is E3 ubiquitin ligase. It is regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. TRIM63 may play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. It may regulate the organization of myofibrils through TTN in muscle cells. TRIM63 is in muscle-specific expression. |
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