IL-1 alpha Recombinant monoclonal antibody proteintech 83644-1-RR
$449.00
In stock
SKU
83644-1-RR
IL-1alpha, Il1a, IL1-alpha, IL-1,IL1, IL1 alpha
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: mouse | Immunogen: Recombinant protein Predict reactive species |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 31kd |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_010554 |
| Conjugate: Unconjugated | Gene Symbol: Il1a |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 16175 |
| Application: Western Blot (WB) | RRID: AB_3671254 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Interleukin-1α (IL-1 Alpha) is a protein that plays a crucial role in the regulation of a number of key cellular processes. IL-1 Alpha is a cytokine and a potent mediator of body's response to inflammation, microbial invasion, tissue injury and immunological response. In addition, recent studies suggest that IL-1 Alpha also has a role in wound healing, rheumatoid arthritis, Alzheimer's disease and tumor growth. IL-1 Alpha functions as an alarmin during the process of sterile inflammation. It serves as a signal from dying cells to potentiate the inflammatory response, increasing the expression of other secreted factors like IL-6 and IL-8. IL-1 Alpha was found to affect the cell cycle of osteosarcoma cell to reduce cell growth. IL-1 Alpha is initially translated as approximately 30-kD polypeptides that are processed to approximately 17.5-kD polypeptides prior to, or during, release from macrophages. |
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