Phospho-CREB1 (Ser133) Polyclonal antibody proteintech 28792-1-AP
$449.00
In stock
SKU
28792-1-AP
CREB1 (Ser133), p CREB1, p CREB1 (Ser133), p CREB1 Ser133, p-CREB1
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse, rat | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 341 aa, 35 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC010636 |
| Conjugate: Unconjugated | Gene Symbol: CREB1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1385 |
| Application: Western Blot (WB) | RRID: AB_2918203 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: The cAMP-response element binding protein (CREB) is localized in the nucleus and acts as a transcription factor, which binds to the cAMP response element (CRE) of the promoters of its target genes, upon phosphorylation at Ser133 by different receptor-activated protein kinases, such as protein kinase A (PKA), calmodulin-dependent protein kinase (CaMK), mitogen-activated protein kinases (MAPK), and other kinases. The activity of CREB1 in neurons has been correlated with various intracellular processes, including proliferation, differentiation, survival, long-term synaptic potentiation, neurogenesis, and neuronal plasticity. CREB1 belongs to the CREB/activating transcription factor (ATF) family of transcription factors. (PMID:?30214393, PMID:?33917483, PMID:?32605164) The antibody also detects the phosphorylated form of the CREB-related protein ATF1. |
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