CD155/PVR Recombinant monoclonal antibody proteintech 83724-6-RR
$449.00
In stock
SKU
83724-6-RR
Pvr, Tage4, poliovirus receptor, CD155, 240731B1
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: Mouse And More (1) | Immunogen: Recombinant protein Predict reactive species |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 45 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_027514.2 |
| Conjugate: Unconjugated | Gene Symbol: CD155/PVR |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 52118 |
| Application: Western Blot (WB) | RRID: AB_3671324 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: CD155, also known as the poliovirus receptor (PVR) or Necl-5, is one of the nectin-like family members, belonging to the Ca2+ independent immunoglobulin superfamily (IgSF) in cell adhesion molecules (PMID: 37660884). CD155 is a type I transmembrane protein composed of three extracellular immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic tail. It is involved in cell-to-cell and cell-to-ECM adhesion (PMID: 32019260; 11437656). CD155 acts as a ligand for immune receptors, including TIGIT, CD96 and CD226, which are expressed on T cells and NK cells. CD155 interacts with these receptors to modulate immune responses, such as T cell activation and NK cell-mediated cytotoxicity (PMID: 37660884). CD155 serves as the entry receptor for poliovirus and thereby mediates susceptibility to poliovirus infection (PMID: 15034010). |
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