ASGR1 Recombinant monoclonal antibody proteintech 83691-3-RR
$449.00
In stock
SKU
83691-3-RR
asialoglycoprotein receptor 1, HL-1, 240672C4, ASGP R 1, ASGPR
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: human, rat | Immunogen: CatNo: Eg0946 Product name: Recombinant Human ASGR1 protein (His Tag) Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS Tag: N-6*His Domain: 62-291 aa of NM_001671.4 Sequence: QNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL Predict reactive species |
| Applications: WB, IF-P, ELISA | Observed Molecular Weight: 33 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_001671.4 |
| Conjugate: Unconjugated | Gene Symbol: ASGR1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 432 |
| Application: Western Blot (WB) | RRID: AB_3671295 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. |
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