Phospho-AMPK Beta 1 (Ser182) Recombinant monoclonal antibody proteintech 83924-1-RR
$449.00
In stock
SKU
83924-1-RR
AMPKβ1 (Ser182), AMPKβ1Ser182, p AMPK, p AMPK Beta 1, p AMPK Beta 1 (Ser182)
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: Human And More (3) | Immunogen: Peptide Predict reactive species |
| Applications: WB, ELISA | Observed Molecular Weight: 38 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC001007 |
| Conjugate: Unconjugated | Gene Symbol: PRKAB1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 5564 |
| Application: Western Blot (WB) | RRID: AB_3671504 |
| Dilution: WB : 1:500-1:1000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: AMPK Beta 1 (5'-AMP-activated protein kinase subunit beta-1) is also named as?PRKAB1 and AMPK. AMPK, a serine/threonine kinase that exists as a heterotrimer comprised of a catalytic α-subunit and regulatory β- and γ-subunits, has been recognized as a sensor of cellular energy homeostasis (PMID: 21937710). AMPK regulates key metabolic enzymes, cell growth, apoptosis, gene transcription, and protein synthesis (PMID: 12829246). AMPK is an energy sensor and plays an essential role in the control of cellular bioenergetics by responding to various stresses including those that induce changes in the cellular AMP:ATP ratio or modulation in intracellular calcium (PMID: 27812976, PMID: 26616193). Recent studies have shown that AMPK mediates the inhibition of cell proliferation and growth of tumor cells (PMID: 16613876). AMPK also inhibits the expression of Glut1 and glycolysis in Tregs by inhibiting mTORC1 signaling (PMID: 25477880). This antibody recognizes phosphorylated AMPK Beta 1. |
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