VCAM-1/CD106 Recombinant monoclonal antibody proteintech 84249-4-RR
$449.00
In stock
SKU
84249-4-RR
VCAM1, VCAM-1, 241284B2, CD106, INCAM 100
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: vascular cell adhesion molecule 1 |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 100 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: VCAM-1 |
| Conjugate: Unconjugated | Gene Symbol: 7412 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671799 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843). |