NKp46/NCR1 Recombinant monoclonal antibody proteintech 84416-5-RR
$449.00
In stock
SKU
84416-5-RR
241811H7, Activating receptor 1, Ar1, CD335, Kilr1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: mouse, rat | Immunogen: natural cytotoxicity triggering receptor 1 |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 50-60 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NKp46/NCR1 |
| Conjugate: Unconjugated | Gene Symbol: 117547 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671945 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Liquid |
| Tested Reactivity: Mouse, Rat | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets, and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098). |
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