Kv4.2 Recombinant monoclonal antibody proteintech 85133-3-RR
$449.00
In stock
SKU
85133-3-RR
KCND2, 242754F4, KIAA1044, Potassium voltage-gated channel subfamily D member 2, RK5
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: potassium voltage-gated channel, Shal-related subfamily, member 2 |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 75 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: KCND2 |
| Conjugate: Unconjugated | Gene Symbol: 3751 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse | Form: Q9NZV8 |
| Host / Isotype: Recombinant | Background Information: Voltage-gated potassium or Kv channels, specifically those mediating low threshold, rapidly inactivating Ito and IA currents, are known to regulate cardiac and neuronal membrane excitability, respectively (PMID: 12829703). Voltage-gated potassium channel subunit Kv4.2, encoded by the KCND2 gene, belongs to the potassium channel family and D (Shal) subfamily. It is a pore-forming alpha subunit of voltage-gated rapidly inactivating A-type potassium channels. Kv4.2 is highly expressed in the brain (PMID: 10551270). It is a major constituent of A-type potassium currents and a key regulator of neuronal membrane excitability (PMID: 22539834). |
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