CUL1 Recombinant monoclonal antibody proteintech 82474-1-RR
$449.00
In stock
SKU
82474-1-RR
Cullin-1, Cullin1, CUL-1, 5K17
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: Human, rat, mouse | Immunogen: cullin 1 |
| Applications: WB, IP, ELISA | Observed Molecular Weight: 90 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CUL1 |
| Conjugate: Unconjugated | Gene Symbol: 8454 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3086481 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:17000 | Conjugate: Liquid |
| Tested Reactivity: Human, Rat, Mouse | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases. Humans express seven cullin proeins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality. |
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