CHCHD2 Recombinant monoclonal antibody proteintech 82702-1-RR
$449.00
In stock
SKU
82702-1-RR
HCV NS2 trans-regulated protein, Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, C7orf17, Aging-associated gene 10 protein, AAG10
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, rat | Immunogen: coiled-coil-helix-coiled-coil-helix domain containing 2 |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 16 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CHCHD2 |
| Conjugate: Unconjugated | Gene Symbol: 51142 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3086512 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CHCHD2 is a widely expressed 16.7-kDa mitochondrion-localized protein. CHCHD2 contains a C-terminal CHCH (coiled-coil helix coiled-coil helix) domain. Mutations in CHCHD2 gene have been reported in autosomal dominant Parkinson's disease (ADPD). CHCHD2 is a bi-organellar mediator of oxidative phosphorylation, playing crucial roles in regulating electron flow in the mitochondrial electron transport chain and acting as a nuclear transcription factor for a cytochrome c oxidase subunit (COX4I2) and itself in response to hypoxic stress. CHCHD2 also regulates cell migration and differentiation, mitochondrial cristae structure, and apoptosis (PMID: 33967741). |
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